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Lipoprotein(a) — The Blood Test That Can Change Your Cardiovascular Risk Sydney CBD

Dr. Georgia Wyatt

Established 2004

Last updated:

Lipoprotein(a) scientific diagram with labels

This blood test can significantly change how we assess cardiovascular risk — and many patients have never had it measured.

It’s called Lipoprotein(a), or Lp(a), and most standard cholesterol panels don’t include it.

Why this matters

You can eat well, exercise regularly, and have “normal” cholesterol levels — and still carry elevated cardiovascular risk.

Lp(a) is largely genetic, meaning lifestyle changes alone may not fully explain your risk profile.

What is Lipoprotein(a)?

Lipoprotein(a) is a cholesterol-related particle linked to cardiovascular disease. Unlike standard cholesterol markers, it is largely genetically determined.

You are born with your level, it remains relatively stable over time, and in most cases only needs to be measured once.

Why it changes management

Elevated Lp(a), seen in around 1 in 5 people, can significantly influence how cardiovascular risk is interpreted.

  • Amplifies the impact of LDL cholesterol
  • Accelerates atherosclerosis
  • Increases the risk of heart attack and stroke

This can change treatment targets and determine whether more aggressive prevention is appropriate.

You can learn more about our approach to testing here: Blood tests Sydney

Dr Georgia Wyatt, CEO and Medical Director of Executive Medicine

About the Author

Dr Georgia Wyatt

CEO and Medical Director of Executive Medicine

Dr Georgia Wyatt is CEO and Medical Director of Executive Medicine, a Sydney CBD clinic established in 1985. She is a Fellow of the Royal Australian College of General Practitioners with additional training in tropical medicine and child health. Her clinical focus is on early detection, preventative care and long-term health planning, with an emphasis on structured, evidence-based assessment and continuity of care. Dr Wyatt’s approach centres on identifying meaningful risk patterns early and translating them into clear, practical strategies that support long-term health and performance.